II.
Paracoccidioidomycosis
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Case 15:
Paracoccidioidomycosis / Carcinoma
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Paracoccidioidomycosis
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Carcinoma
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![Click here to see the picture 15-A1](figuras/15-0001p.jpg) Fig.15-A1 Paracoccidioidomycosis
A 45-years old worker from the vicinity of the town Barinas / Venezuela complains for several months about toothache and ulceration at the right side of his tongue, which is growing continuously. Furthermore, some enlarged lymph nodes are palpable at the lower yaw border. The tongue is thickened and the ulcer is hardly seen.
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![Click here to see the picture 15-B1](figuras/15-0004p.jpg) Fig.15-B1 Carcinoma
A 22 -year old man presents a painless ulcer at the right side of his tongue growing slowly. All kinds of treatment were unsuccessful.
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![Click here to see the picture 15-A2](figuras/15-0002p.jpg) Fig.15-A2 Paracoccidioidomycosis
A biopsy taken from the border of the ulcer of the tongue shows a cell-rich granulation tissue with giant cells containing roundish, optically empty elements. HE stain, low power magnification.
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![Click here to see the picture 15-B2](figuras/15-0005p.jpg) Fig.15-B2 Carcinoma
The histological examination of a biopsy from the border of the tongue ulcer revealed a non-cornified squamous cell carcinoma.
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![Click here to see the picture 15-A3](figuras/15-0003p.jpg) Fig.15-A3 Paracoccidioidomycosis
The round, optically empty elements turn out to be typical yeast cells of Paracoccidioides brasiliensis partly with multiple budding. GMS stain.
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