II.
Paracoccidioidomycosis
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Case 20:
Paracoccidioidomycosis / Melanoma
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Paracoccidioidomycosis
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Melanoma
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Fig.20-A1 Paracoccidioidomycosis
A merchant from Mérida / Venezuela noted a tumor-like, ulcerated skin lesion at his left plantar surface which had grown slowly during some months. The doctor who was consulted made a smear from the ulcer surface without staining it. The result will be shown in Fig. 20-A2.
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Fig.20-B1 Melanoma
A farmer living near the town of Mérida in Venezuela noted a slowly growing tumor-like swelling in the posterior parts of his left sole. The skin of this tumor was partly blackish and partly ulcerated.
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Fig.20-A2 Paracoccidioidomycosis
In this smear a structure was found which resembled the steering wheel form of a budding Paracoccidioides brasiliensis cell, however, it could represent air bubbles.
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Fig.20-B2 Melanoma
Histology revealed a malignant tumor of this kind.
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Fig.20-A3 Paracoccidioidomycosis
In the culture of the material taken from the ulcer surface did grow colonies of Paracoccidioides brasiliensis.
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Fig.20-A4 Paracoccidioidomycosis
The patient suddenly accused pain at his left lower extremity. In the x-ray examination of the fibula a localized defect was detected which represented a osteomyelitis caused by this fungus. This confirmed a marked haematogenous dissemination of P. brasiliensis.
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Fig.20-A5 Paracoccidioidomycosis
In an enlarged axillary lymph node also was found a fungal infection with P. brasiliensis which had produced necrotic and caseating foci.
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