Fig.43-A1
Sporotrichosis

A 35-year old farmer from the environs of the town Barinas / Venezuela noted since more or less ten months the development of a warty skin lesion on the tip of his nose. It was painless and not itching. Small skin defects were covered by crusts.

Fig.43-A2
Sporotrichosis

With the HE stain of the biopsy acanthosis and pseudoepitheliomatous hyperplasia of the epidermis was detected and in the dermis a non-specific inflammation with giant cells and microabscesses was observed. Fungus cells were not seen.

Fig.43-A3
Sporotrichosis

Histologically fungus cells could not be detected inspite of a long search. In our cases of human infections with Sporothrix schenckii we never have seen fungi in tissues. Exceptionally there are present in large numbers in cases of a local immunodeficiency for instance after a treatment with cortisone in ointments.

Fig.43-A4
Sporotrichosis

The culture of Sporothrix schenckii had grown at 25º C on Carrot-Agar after 28 days.

Fig.43-A5
Sporotrichosis

In smears of the culture colony of fig 43-A4 the mycelial form of S. schenckii with thin hyphae and conidias arranged in daisy -like structures are seen.